Description
General Description
PEI-g-PEG, or polyethylenimine-graft-PEG, is a graft copolymer consisting of a cationic PEI backbone functionalized with hydrophilic PEG chains.
PEI contains multiple primary, secondary, and/or tertiary amines depending on its structure and molecular weight. These amines provide positive charge under suitable conditions and can interact electrostatically with negatively charged molecules such as DNA, RNA, and other polyanions.
Grafting PEG onto PEI introduces hydrophilic polymer chains that can modify the solubility, surface properties, aggregation behavior, and interactions of PEI-based materials with biological environments.
NSP offers PEI-g-PEG with different PEI molecular weights, PEG molecular weights, and PEG grafting levels for research applications.
Applications
- DNA and RNA complexation
- Gene delivery research
- Nucleic acid delivery
- Polyplex preparation
- Nanoparticle formulation
- Nanoparticle surface modification
- Biomaterials research
- Polymer conjugation
- Surface coating
- Drug delivery research
- Cationic polymer research
Features and Benefits
- PEI backbone with PEG grafts
- Cationic amine-rich polymer
- Hydrophilic PEG side chains
- Combines properties of PEI and PEG
- Suitable for nucleic acid complexation
- Useful for nanoparticle modification
- Adjustable PEI molecular weight
- Adjustable PEG molecular weight
- Custom PEG grafting density available
- Custom compositions available
