Product Description
Thiol capped 4-arm poly(lactide-co-glycolide) (4-arm PLGA thiol, 4-arm PLGA-SH is a multiarm PLGA derivative with -SH groups at each terminal of the four arms connected to one pentaerythritol core. The reactive free thiol, SH, sulfhydryl, or mercapto groups selectively react with maleimide and transition metal surface including gold, silver, etc. PLGA-SH can be easily air oxidized to form S-S disulfide (disulphide) bonds, which can be reversed with reducing agents. Otherwise noted, multiarm PLGA is composed of d,l-lactide and glycolide (50:50 ratio).
