DOPE-PEG-Amine

$385.00 – $1,200.00

 

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SKU: 13423 Categories: , ,

Product Description

1,2-Dioleoyl-sn–glycero-3-phosphoethanolamine (DOPE)-polyethylene glycol-amine (DOPE-PEG-Amine, DOPE-PEG-NH2) is a linear heterobifunctional PEGylation reagent with an unsaturated  DOPE phospholipid and an amine. DOPE-PEG-NH2 is used to modify liposome surface with biomolecules containing amine reactive groups (NHS, thiolate). It is a useful self-assembling reagent to prepare grafted or PEGylated liposome or micelle while also providing an amine group for bioconjugation. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the amine group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide.

Additional information

Molecular weight

1000, 2000, 3400, 5000
Package size

100 mg, 500mg, 1g
Appearance: Solid powder or chunk, white to off white.
Purity: >90% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 – 4°C for short term (days to weeks) or -20°C for long term (months to years).
Solubility: Soluble in DMSO, dichloromethane, chloroform, acetone, and DMF
Stock Solution Storage: 0 – 4°C for short term (days to weeks), or -20°C for long term (months).

 

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