DSPE-PEG-Ald

$220.00$1,100.00

DSPE-PEG-Ald

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-poly(ethylene glycol)-aldehyde

 

 

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SKU: 25224 Categories: , ,

Product Description

1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated Polyethylene Glycol aldehyde (DSPE-PEG-Ald),  is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.

PEG aldehyde or ketone derivatives can be used in reversible PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage.

Additional information

Molecular weight

1000, 2000, 3400, 5000

Package size

100mg, 500mg, 1g

Appearance: Solid powder or chunk, white to off white to slight yellow.
Purity: >90% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 – 4°C for short term (days to weeks) or -20°C for long term (months to years).
Solubility: Soluble in DMSO, dichloromethane, chloroform, acetone, and DMF