DSPE-Polysarcosine

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Product Description

DSPE-polysarcosine (DSPE-pSar) is a lipid-polypeptoid conjugate based on the endogenous amino acid sarcosine (N-methylated glycine), which has previously shown potent stealth properties. As a polymer, pSar combines PEG-like properties, e.g., excellent solubility in water, protein resistance, low cellular toxicity and a non-immunogenic character, while being based on endogenous material. Recently it was gained broader attention and is considered a potential alternative of poly(ethylene glycol) (PEG).

DSPE-polysarcosine can be used to prepupae stealth nanoparticles which are potentially an alternative of PEG modification.

 

Additional information

Molecular Weight

1400 (n=20), 3500 (n=50), 7000(n=100), 10.6K(n=150)

Package size

50mg, 100mg, 500mg