Product Description
Poly(L-Lysine)-poly(ethylene glycol)-Ortho-Pyridyldisulfide (PLL-PEG-OPSS) is amphiphilic block copolymer that has PLL as the core-forming block and azide-functionalized PEG as the shell-forming block. PLL-PEG-OPSS has pendant free amine in PLL block and Ortho-Pyridyldisulfide in PEG block. it can self assemble into micelle with OPSS on the micelle surface for shell modification.
Ortho-pyridyl disulfide (OPSS) reacts with thiol groups to form a stable disulfide bond, while releasing a thiol pyridyl group. This reaction can be used to modify biomolecules and other materials that have thiol groups. OPSS can also react with sulfhydryl or mercapto to form a reversible disulfide bond.
