DOPA structure

DOPA

Price range: $160.00 through $1,600.00

DPPA (1,2-Dipalmitoyl-sn-glycero-3-phosphate, sodium salt; 16:0 PA) is a synthetic phosphatidic acid lipid containing two saturated palmitoyl (C16:0) chains and a negatively charged phosphate head group. DPPA is widely used in liposome preparation, lipid nanoparticle formulation, membrane biophysics studies, drug delivery research, and lipid-protein interaction investigations.

Product Specifications

Product Name: DOPA
Chemical Name: 1,2-Dioleoyl-sn-glycero-3-phosphate, sodium salt
Abbreviation: DOPA (18:1PA)
Molecular Weight: 670.87 
Cas#: 108392-02-5
Appearance: White to off-white powder
Solubility: Chloroform, Methanol, Chloroform/Methanol mixtures
Storage: -20°C, dry and protected from light
Purity: 97%

DOPA structure

 

SKU: 13960 Categories: , ,

Product Details

CAS No. : 18194-24-6
Formula : C36H72NO8P
M.W : 677.93
SMILES Code : CCCCCCCCCCCCCC(O[C@@H](COP([O-])(OCC[N+](C)(C)C)=O)COC(CCCCCCCCCCCCC)=O)=O
Synonyms :
DMPC; Dimyristoyl phosphatidylcholine; 1,2-Dimyristoyl-sn-glycero-3-phosphorylcholine
English Name : (R)-2,3-Bis(tetradecanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
MDL No. : MFCD00036901
InChI Key : CITHEXJVPOWHKC-UUWRZZSWSA-N
Pubchem ID : 5459377

Description

General Description

DOPA is an anionic phospholipid belonging to the phosphatidic acid (PA) family. It consists of two oleic acid (C18:1) chains esterified to a glycerol backbone and a phosphate head group present as the sodium salt.

Due to its unsaturated acyl chains, DOPA exhibits greater membrane fluidity than saturated phosphatidic acid lipids such as DPPA and DSPA. DOPA is frequently utilized in lipid bilayer studies, membrane fusion investigations, liposome formulation, and lipid nanoparticle development.

DOPA is particularly valuable in the preparation of lipid-coated calcium phosphate nanoparticles and other nanomedicine platforms used for nucleic acid delivery, imaging, and therapeutic applications.

Applications

  • Liposome formulation
  • Lipid nanoparticle (LNP) research
  • Calcium phosphate nanoparticle synthesis
  • Membrane fusion studies
  • Model membrane preparation
  • Lipid-protein interaction studies
  • Drug delivery research
  • Gene delivery research
  • Nanomedicine development
  • Pharmaceutical formulation research

Features and Benefits

  • Synthetic phosphatidic acid lipid
  • Negatively charged phospholipid
  • Unsaturated C18:1 acyl chains
  • Enhanced membrane fluidity
  • Suitable for liposome preparation
  • Widely used in nanoparticle formulation
  • Compatible with lipid nanoparticle systems
  • Excellent batch-to-batch consistency

Additional information

Package Size

100mg, 200mg, 500mg, 1g, 5g

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