DPPA structure

DPPA

Price range: $160.00 through $1,600.00

DPPA (1,2-Dipalmitoyl-sn-glycero-3-phosphate, sodium salt; 16:0 PA) is a synthetic phosphatidic acid lipid containing two saturated palmitoyl (C16:0) chains and a negatively charged phosphate head group. DPPA is widely used in liposome preparation, lipid nanoparticle formulation, membrane biophysics studies, drug delivery research, and lipid-protein interaction investigations.

Product Specifications

Product Name: DSPA
Chemical Name: 1,2-Dipalmitoyl-sn-glycero-3-phosphate, sodium salt
Abbreviation: DPPA (16:0 PA)
Molecular Weight: 670.87 
Cas#: 169051-60-9
Appearance: White to off-white powder
Solubility: Chloroform, Methanol, Chloroform/Methanol mixtures
Storage: -20°C, dry and protected from light
Purity: 97%

DPPA structure

 

SKU: 13958 Categories: , ,

Product Details

CAS No. : 18194-24-6
Formula : C36H72NO8P
M.W : 677.93
SMILES Code : CCCCCCCCCCCCCC(O[C@@H](COP([O-])(OCC[N+](C)(C)C)=O)COC(CCCCCCCCCCCCC)=O)=O
Synonyms :
DMPC; Dimyristoyl phosphatidylcholine; 1,2-Dimyristoyl-sn-glycero-3-phosphorylcholine
English Name : (R)-2,3-Bis(tetradecanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
MDL No. : MFCD00036901
InChI Key : CITHEXJVPOWHKC-UUWRZZSWSA-N
Pubchem ID : 5459377

Description

General Description

DPPA is an anionic phospholipid belonging to the phosphatidic acid (PA) family. It consists of two palmitic acid (C16:0) chains esterified to a glycerol backbone and a phosphate head group present as the sodium salt.

Phosphatidic acid lipids are important structural and signaling molecules involved in membrane curvature, vesicle trafficking, membrane fusion, and cellular signaling pathways. DPPA is frequently utilized in liposome formulation, model membrane systems, pharmaceutical formulations, and nanomedicine research due to its well-defined composition and high purity.

As a fully saturated phospholipid, DPPA contributes to membrane stability and is widely employed in studies involving lipid bilayers, membrane dynamics, and lipid-based drug delivery systems.

Applications

  • Liposome formulation
  • Lipid nanoparticle (LNP) research
  • Model membrane preparation
  • Membrane fusion studies
  • Lipid-protein interaction studies
  • Drug delivery research
  • Lipid metabolism research
  • Cell membrane biophysics
  • Nanomedicine development
  • Pharmaceutical formulation research

Features and Benefits

  • Synthetic phosphatidic acid lipid
  • Negatively charged phospholipid
  • Fully saturated C16:0 acyl chains
  • High membrane stability
  • Suitable for liposome preparation
  • Useful for membrane biophysics studies
  • Compatible with lipid nanoparticle formulations
  • Excellent batch-to-batch consistency

Additional information

Package Size

100mg, 200mg, 500mg, 1g, 5g

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