Description
General Description
DSPE-Alkyne is a reactive phospholipid derivative containing DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine, C18:0) and a terminal alkyne functional group. The alkyne functionality enables highly selective click chemistry reactions with azide-containing molecules for bioconjugation and surface modification applications.
Key Properties
- Alkyne-functionalized phospholipid
- Suitable for click chemistry conjugation
- Reactive terminal alkyne group
- DSPE phospholipid anchor (C18:0)
- Saturated lipid structure for enhanced membrane stability
Applications
- Click chemistry conjugation
- Liposome surface modification
- Lipid nanoparticle engineering
- Drug and nucleic acid delivery
- Biomolecule and nanoparticle functionalization
- Nanomedicine and biomaterial applications
Functional Overview
The DSPE lipid segment provides stable membrane incorporation, while the terminal alkyne group enables selective conjugation with azide-containing molecules through click chemistry reactions.
Summary
DSPE-Alkyne is a versatile click-reactive phospholipid widely used in liposome engineering, nanoparticle functionalization, and advanced nanomedicine applications
