DSPE phospholipid structure

DSPE

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DSPE phospholipid structure

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Product Details

Product Details of 1,2-Distearoyl-sn-glycero-3-phosphorylcholine

CAS No. : 816-94-4
Formula : C44H88NO8P
M.W : 790.15
SMILES Code : O=P(OC[C@H](OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)([O-])OCC[N+](C)(C)C
Synonyms :
1,2-Distearoyl-sn-glycero-3-PC; DSPC; Coatsome MC 8080
English Name : (R)-2,3-Bis(stearoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
MDL No. : MFCD00036905
InChI Key : NRJAVPSFFCBXDT-HUESYALOSA-N
Pubchem ID : 94190

Description

General Description

DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is a saturated phospholipid containing two C18:0 stearic acid chains and a phosphoethanolamine head group. Due to its high membrane stability and hydrophobic lipid structure, DSPE is widely used in liposome formulation, lipid nanoparticles (LNPs), drug delivery systems, and membrane engineering applications.

Key Properties

  • Saturated phospholipid (C18:0)
  • High membrane stability
  • Suitable for liposome and nanoparticle formulation
  • Hydrophobic lipid bilayer component
  • Widely used in nanomedicine and drug delivery systems

Applications

  • Liposome formulation
  • Lipid nanoparticle (LNP) engineering
  • Drug delivery systems
  • Membrane stabilization
  • Nanomedicine applications
  • Biomaterial and lipid bilayer research

Functional Overview

DSPE serves as a stable phospholipid building block for lipid bilayers, liposomes, and nanoparticle systems. Its saturated lipid chains contribute to enhanced membrane rigidity and formulation stability.

Summary

DSPE is a versatile saturated phospholipid widely used in liposome engineering, lipid nanoparticle development, and advanced drug delivery research applications.

Additional information

Package Size

100mg, 200mg, 500mg, 1g, 5g

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