MPEG-PCL structure

MPEG-PCL

Price range: $260.00 through $960.00

mPEG-PCL (Methoxy Polyethylene Glycol-b-Polycaprolactone) is a tin-free, biodegradable amphiphilic block copolymer composed of methoxy polyethylene glycol (mPEG) and polycaprolactone (PCL). The hydrophobic PCL segment enables efficient encapsulation of hydrophobic drugs, while the hydrophilic PEG segment improves aqueous solubility, colloidal stability, and biocompatibility. mPEG-PCL is widely used for polymeric micelles, nanoparticle fabrication, drug delivery, and biomedical research applications.

Product Specifications

Product Name: mPEG-PCL
Polymer Composition: Methoxy Polyethylene Glycol-b-Polycaprolactone
Molecular Weight: Custom PEG and PCL molecular weights available
Functional Groups: Methoxy (mPEG terminus)
Appearance: White to off-white solid
Solubility: Water, DMSO, DMF, THF, Chloroform
Storage: -20°C, dry and protected from light
Purity: Typically ≥95%

MPEG-PCL structure

SKU: 12833 Categories: , ,

Description

General Description

mPEG-PCL is a biodegradable diblock copolymer extensively utilized in nanomedicine and controlled drug delivery systems. Due to its amphiphilic nature, mPEG-PCL self-assembles in aqueous environments to form polymeric micelles and nanoparticles with a hydrophobic PCL core and a hydrophilic PEG shell.

The PCL block exhibits excellent biocompatibility and slow biodegradation characteristics, making mPEG-PCL particularly suitable for sustained drug release applications. The PEG corona reduces protein adsorption, improves colloidal stability, and prolongs circulation time. mPEG-PCL has been widely investigated for the delivery of anticancer drugs, proteins, peptides, and imaging agents.

Applications

  • Polymeric micelle preparation
  • Nanoparticle fabrication
  • Drug delivery systems
  • Controlled drug release
  • Anticancer drug delivery
  • Protein and peptide delivery
  • Nanomedicine research
  • Biomedical coatings
  • Tissue engineering
  • Imaging agent delivery

Features and Benefits

  • Tin-free synthesis process
  • Biodegradable PCL block
  • Hydrophilic PEG segment improves biocompatibility
  • Self-assembles into polymeric micelles
  • Suitable for hydrophobic drug encapsulation
  • Excellent colloidal stability
  • Prolonged circulation properties
  • Available in multiple molecular weight combinations

Additional information

Molecular Weight-PCL

1000, 2000, 3000, 4000, 5000, 6000, 8000, 10k
Molecular weight-PEG

1000, 2000, 5000
Package size

1g, 10g

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