Research Using NSP Products

Selected publications featuring NSP products.

YearPublicationNSP product identified
2026E-selectin and transferrin receptor functionalized synthetic miRNA nanoshuttles with therapeutic potential in strokeDSPE-PEG2000-Maleimide and DLin-MC3-DMA — NanoSoft Polymers. Published July 14, 2026. (Springer)
2026Real-time in vivo tracking of nanoparticulate vaccines in inguinal lymph nodesPLGA10K-PEG2K-Mal — Nanosoft Polymers. (Springer)
2026In vitro evaluation of PEI-coated microbubble–neutrophil conjugates for ultrasound-guided cell deliveryN3-PEI-PEG, PEI 10K/PEG 2K, 20% substitution — Nanosoft Polymers. (Frontiers)
2026Kidney-Targeted Nanoparticle Delivery of Formoterol Mitigates Diabetic Kidney Disease without Adverse Cardiac EffectsPLGA20K-PEG5K-NH2, 50:50 — Nanosoft Polymers. (ACS Publications)
2026Single-molecule readout of reversible nanoswitches enables continuous monitoring of low biomarker concentrationsPLL(15)-g[5]-PEG(2)-N3 — Nanosoft Biotechnology LLC. (Nature)
2025End group chemistry modulates physical properties and biomolecule release from biodegradable polyestersPLGA5K-COOH, PLGA5K-NH2 and PLGA5K-OH, 50:50 — Nanosoft Polymers. (PubMed Central (PMC))
2025Biologically targeted dual adaptive and innate nano-Immunotherapy for clear cell renal cell carcinoma treatmentN3-PEG3K-PLGA10K, catalog 2774-10k-3000-1g — Nanosoft Polymers. (PubMed Central (PMC))
2025Engineering Lipid–Polymer Nanoparticles for siRNA Delivery to Cancer CellsDLin-MC3-DMA, SKU 25325 — Nanosoft Biotechnology LLC. (PubMed Central (PMC))
2025Citrus pectin-coated inhalable PLGA nanoparticles for treatment of pulmonary fibrosisPLGA-NH2·HCl, 10K, 50:50 — Nanosoft Polymers. (PubMed Central (PMC))
2025Nanoparticle-boosted myeloid-derived suppressor cell therapy for immune reprogramming in multiple sclerosisPLGA20K-PEG5K-DBCO and mPEG2K-PLGA20K — Nanosoft Polymers. (PubMed Central (PMC))
2025Spatial Molecular Heterogeneity on Biofunctionalized Particles Quantified by Three-Dimensional Single-Molecule DNA-PAINTPLL-g-PEG-N3, PLL 15K/PEG 2K/grafting ratio 5 — Nanosoft Biotechnology LLC. (PubMed Central (PMC))
2025Temperature-Dependent Stability of Components in a Particle-based Continuous BiosensorN3-PLL-g-PEG — Nanosoft Biotechnology LLC. (Wiley Online Library)
2025Development of DNase-1 Loaded Polymeric Nanoparticles Synthesized by Inverse Flash Nanoprecipitation for Neutrophil-Mediated Drug Delivery to in vitro ThrombiPLLA5K-PEG5K-Maleimide — Nanosoft Polymers. (PubMed Central (PMC))
2025Novel Tissue-Specific Multifunctionalized Nanotechnological Platform Encapsulating Riluzole Against Motor Neuron DiseasesPLGA-Maleimide and CH3-PEG — Nanosoft Polymers. (PubMed Central (PMC))
2024Revealing Spatial Molecular Heterogeneity of High-Density Biofunctionalized Surfaces Using DNA-PAINTAzide-functionalized PLL-g-PEG, PLL 15K/PEG 2K/grafting ratio 5 — Nanosoft Biotechnology LLC. (PubMed Central (PMC))
20243D Printing as a Strategy to Scale-Up Biohybrid Hydrogels for T Cell Manufacture4-arm thiol-terminated PEG/PEO, MW 10K — Nanosoft Biotechnology LLC. (PubMed Central (PMC))
2024PDZ2-conjugated-PLGA nanoparticles are tiny heroes in the battle against SARS-CoV-2PLGA-COOH, 10K — Nanosoft Polymers. (PubMed Central (PMC))
2023Vinyl Sulfone-functionalized Acetalated Dextran Microparticles as a Subunit Broadly Acting Influenza VaccinePLLA-PEG-Vinylsulfone (PLLA-PEG-VS) — Nanosoft Polymers. (PubMed Central (PMC))
2023Biomaterial-targeted precision nanoparticle delivery to the injured spinal cordPLGA10K-PEG2K-COOH — Nanosoft Polymers. (PubMed Central (PMC))
2023Docetaxel-Loaded Methoxy poly(ethylene glycol)-poly(L-lactic Acid) Nanoparticles for Breast CancerPLLA2K-MPEG2K — Nanosoft Biotechnology LLC. (PubMed Central (PMC))
2022Design, Development, Physicochemical Characterization, and In Vitro Drug Release of Formoterol PEGylated PLGA Polymeric NanoparticlesPLGA20K-PEG5K-NH2 and PLGA20K-PEG5K-COOH — Nanosoft Polymers. (PubMed Central (PMC))
2022The influence of Gd-DOTA conjugating ratios to PLGA-PEG micelles encapsulated IR-1061…PLGA2K-PEG2K and PLGA2K-PEG2K-COOH — Nanosoft Polymers. (Royal Society of Chemistry Publishing)
2022Continuous biomarker monitoring with single molecule resolution by measuring free particle motionPLL-g-PEG-N3 — Nanosoft Biotechnology LLC. (PubMed Central (PMC))
2022Direct delivery of plasmin using clot-anchoring thrombin-responsive nanoparticles for targeted fibrinolytic therapyDSPE-PEG2000-NHS — Nanosoft Polymers. (PubMed Central (PMC))
2022Molecular mechanisms of steric pressure generation and membrane remodeling by disordered proteinsVarious DSPE-PEG lipids/PEG10K-NH2 supplied by Nanosoft Polymers. (PubMed Central (PMC))
2021Comparison of PLA-Based Micelles and Microspheres as Carriers of Epothilone B and RapamycinPLA3K-PEG5K — Nanosoft Polymers. (PubMed Central (PMC))
2021The Effect of Surface-Modified Gold Nanorods on the Early Stage of Embryonic Development and AngiogenesisDSPE-PEG-SH and Cholesterol-PEG-SH — Nanosoft Polymers. (PubMed Central (PMC))
2021Development of AE147 Peptide-Conjugated Nanocarriers for Targeting uPAR-Overexpressing Cancer CellsDSPE-PEG-NHS — Nanosoft Biotechnology LLC. (PubMed Central (PMC))
2021Photodynamic and Cold Atmospheric Plasma Combination Therapy Using Polymeric Nanoparticles for the Synergistic Treatment of Cervical CancerMPEG2K-PLGA3K, 50:50 — Nanosoft Polymers. (MDPI)
2020PEGylated PLGA Nanoparticle Delivery of Eggmanone for T Cell Modulation: Applications in Rheumatic AutoimmunityPLGA10K-PEG5K-Maleimide and PLGA10K-PEG5K-Methyl; unusually, the paper even reports NSP lot numbers. (PubMed Central (PMC))
2020Mesenchymal Stem Cells As Guideposts for Nanoparticle-Mediated Targeted Drug Delivery in Ovarian CancerPLA10K-PEG5K-NH2 — Nanosoft Polymers. (PubMed Central (PMC))
2020Micropatterned Poly(ethylene glycol) Islands Disrupt Endothelial Cell–Substrate Interactions Differently from Microporous MembranesPLL(20)-g(3.5)-PEG(2) — Nanosoft Biotechnology LLC. (PubMed Central (PMC))
2020Optimization of cRGDfK ligand concentration on polymeric nanoparticles to maximize cancer targetingH2N-PEG-PLGA, reported MW 4K — Nanosoft Biotechnology. (ScienceDirect)
2020A comparative study of the effect of drug hydrophobicity on nanoparticle drug delivery in vivo using two photosensitizersDSPE-MPEG 5K — Nanosoft Polymers. (ScienceDirect)
2020Lowering glutathione level by buthionine sulfoximine enhances in vivo photodynamic therapy using chlorin e6-loaded nanoparticlesPEG5K-PLA4K — Nanosoft Polymers. (ScienceDirect)
2019Acoustofluidic Synthesis of Particulate NanomaterialsPLGA10K-PEG1K-COOH and PLGA10K-PEG3K-COOH — Nanosoft Polymers. (DOI)
2019Folic Acid Receptor-Mediated Targeting Enhances the Cytotoxicity, Efficacy, and Selectivity of Withania somnifera Leaf ExtractDSPE-PEG-Folate — Nanosoft Polymers. (Frontiers)
2018Co-delivery of Paclitaxel and Everolimus by Polymeric Micelles…PLGA-PEG and PLGA-PEG-FITC — NSP’s archived publication note identifies these as Nanosoft products; DOI 10.1021/acs.molpharmaceut.8b00217. (Nanosoft Polymers (NSP))
2016HER2 Targeting Peptides Screening and Applications in Tumor Imaging and Drug DeliveryDSPE-PEG-Maleimide used to prepare HER2-targeted liposomes — Nanosoft Polymers. (Nanosoft Polymers (NSP))