Description
General Description
8-Arm PLGA-OH is a highly branched biodegradable polyester designed for advanced drug delivery and biomedical applications. The polymer consists of eight PLGA chains attached to a central multifunctional core, creating a star-shaped architecture with multiple terminal hydroxyl groups.
Compared with conventional linear PLGA, 8-Arm PLGA-OH offers increased functionality, improved encapsulation efficiency, and enhanced control over degradation profiles. The terminal hydroxyl groups can be further modified to introduce reactive functionalities such as amine, carboxyl, maleimide, NHS ester, azide, alkyne, biotin, and other groups for specialized applications.
Upon hydrolysis, the polymer degrades into lactic acid and glycolic acid, making it suitable for biodegradable pharmaceutical formulations, regenerative medicine, and biomaterials development.
Applications
- Drug delivery systems
- Polymeric nanoparticles
- Polymeric micelles
- Controlled drug release
- Hydrogel formation
- Tissue engineering
- Regenerative medicine
- Biomaterials engineering
- Surface modification
- Nanomedicine research
Features and Benefits
- Star-shaped eight-arm PLGA architecture
- Biodegradable and biocompatible
- Multiple terminal hydroxyl groups
- Higher functional group density than linear PLGA
- Enhanced drug loading capability
- Tunable degradation properties
- Suitable for hydrogel and nanoparticle fabrication
- Readily functionalized for advanced applications
