DMPA

Price range: $160.00 through $1,600.00

DMPA (1,2-Dimyristoyl-sn-glycero-3-phosphate, sodium salt; 14:0 PA) is a synthetic phosphatidic acid lipid containing two saturated myristoyl (C14:0) chains and a negatively charged phosphate head group. DMPA is widely used in liposome preparation, lipid nanoparticle formulation, membrane biophysics studies, drug delivery research, and lipid metabolism investigations.

Product Specifications

Product Name: DMPA
Chemical Name: 1,2-Dimyristoyl-sn-glycero-3-phosphate, sodium salt
Abbreviation: DMPA (14:0 PA)
Molecular Weight: 617.8 g/mol
Cas#:   80724-31-8
Appearance: White to off-white powder
Solubility: Chloroform, Methanol, Chloroform/Methanol mixtures
Storage: -20°C, dry and protected from light
Purity: 97%

 

 

 

DMPA structure

 

SKU: 13964 Categories: , ,

Product Details

CAS No. : 18194-24-6
Formula : C36H72NO8P
M.W : 677.93
SMILES Code : CCCCCCCCCCCCCC(O[C@@H](COP([O-])(OCC[N+](C)(C)C)=O)COC(CCCCCCCCCCCCC)=O)=O
Synonyms :
DMPC; Dimyristoyl phosphatidylcholine; 1,2-Dimyristoyl-sn-glycero-3-phosphorylcholine
English Name : (R)-2,3-Bis(tetradecanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
MDL No. : MFCD00036901
InChI Key : CITHEXJVPOWHKC-UUWRZZSWSA-N
Pubchem ID : 5459377

Description

General Description

DMPA is an anionic phospholipid belonging to the phosphatidic acid (PA) family. It contains two myristic acid (C14:0) chains esterified to a glycerol backbone and a phosphate head group present as the sodium salt.

As a key membrane lipid, phosphatidic acid plays important roles in membrane curvature, lipid signaling, membrane fusion, and vesicle formation. DMPA is frequently utilized as a model phospholipid in liposome preparation, membrane interaction studies, lipid-protein binding investigations, and nanoparticle formulation development.

Due to its well-defined structure and high purity, DMPA serves as a valuable reagent for pharmaceutical, biochemical, and biophysical research applications.


Applications

  • Liposome formulation
  • Lipid nanoparticle (LNP) research
  • Model membrane preparation
  • Membrane fusion studies
  • Lipid-protein interaction studies
  • Drug delivery research
  • Lipid metabolism research
  • Cell membrane biophysics
  • Nanomedicine development
  • Pharmaceutical formulation research

Features and Benefits

  • Synthetic phosphatidic acid lipid
  • Negatively charged phospholipid
  • High purity research-grade material
  • Suitable for liposome preparation
  • Useful for membrane biophysics studies
  • Well-defined fatty acid composition
  • Compatible with lipid nanoparticle formulations
  • Excellent batch-to-batch consistency

Additional information

Package Size

100mg, 200mg, 500mg, 1g, 5g