Description

1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated polyethylene glycol with iodoacetyl  (DSPE-PEG-IA) is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and an iodoacetyl group.  Iodoacetyl (IA)  is a thiol (-SH) reactive group that can be used to modify biomolecules or other materials via their available thiol groups.  Iodine group can be easily replaced by thiol group to form a stable carbon thiol bond. DSPE-PEG-IA is used to prepare micelles or liposomes with Iodoacetyl group on the particle surface for bioconjugation via thiol substitution.