Acryl-PCL-PEG-Alkyne

Acryl-PCL-PEG-Alkyne

Price range: $360.00 through $380.00

Acryl-PCL-PEG-Alkyne is a multifunctional biodegradable copolymer containing an acrylate group, poly(ε-caprolactone) (PCL), polyethylene glycol (PEG), and a terminal alkyne functionality. The acrylate group enables polymerization and hydrogel formation, the PCL segment provides biodegradability and sustained release properties, the PEG spacer improves biocompatibility and aqueous dispersibility, and the alkyne group enables click chemistry conjugation. Acryl-PCL-PEG-Alkyne is widely used in hydrogel synthesis, drug delivery, tissue engineering, and biomaterials research.

Product Specifications

Product Name: Acryl-PCL-PEG-Alkyne
Polymer Composition: Acrylate-Poly(ε-caprolactone)-Polyethylene Glycol-Alkyne
Molecular Weight: PCL (1k-50k), PEG (1k, 2k, 3.4k, 5k, 10k Da), Custom
Functional Groups: Acrylate, PCL, PEG, Alkyne
Appearance: White to off-white solid
Solubility: DMSO, DMF, THF, Dichloromethane, Chloroform, Acetone
Storage: -20°C, dry and protected from light
Purity: Typically ≥95%

Acrl-PCL-PEG-ALK

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SKU: 9210 Categories: , , ,

Description

General Description

Acryl-PCL-PEG-Alkyne is a heterotelechelic biodegradable copolymer designed for advanced biomaterials engineering and bioorthogonal conjugation applications. The acrylate functionality readily participates in free-radical polymerization, photopolymerization, and hydrogel crosslinking reactions, enabling incorporation into polymer networks and injectable biomaterials.

The PCL segment provides a biodegradable hydrophobic domain capable of modulating mechanical properties and degradation behavior, while the PEG segment improves hydrophilicity, biocompatibility, and flexibility. The terminal alkyne group serves as a highly versatile bioorthogonal handle for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and related click chemistry reactions with azide-containing molecules.

Acryl-PCL-PEG-Alkyne is frequently employed in hydrogel fabrication, tissue engineering scaffolds, nanoparticle functionalization, drug delivery systems, and advanced biomedical materials.

Applications

  • Hydrogel synthesis
  • Photopolymerization
  • Injectable hydrogels
  • Tissue engineering
  • Drug delivery systems
  • Click chemistry conjugation
  • Surface modification
  • Nanoparticle functionalization
  • Biomaterials development
  • Regenerative medicine research

Features and Benefits

  • Reactive acrylate functionality
  • Biodegradable PCL segment
  • Hydrophilic PEG spacer
  • Terminal alkyne group for click chemistry
  • Compatible with CuAAC conjugation
  • Suitable for hydrogel formation
  • Excellent biocompatibility
  • Tunable degradation properties
  • Available in multiple molecular weights

Additional information

PCL Molecular Weight

10000, 5000
PEG Molecular Weight

5000, 3400, 2000
Package Size

100 mg

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