Description
General Description
N3-PEG-N3 is a versatile homobifunctional PEG linker designed for bioorthogonal conjugation and crosslinking applications. The two terminal azide groups provide highly selective reactive sites for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC).
The hydrophilic PEG spacer improves water solubility, flexibility, biocompatibility, and reduces nonspecific protein adsorption. N3-PEG-N3 can be utilized as a crosslinker, spacer, surface modifier, or building block for the preparation of hydrogels, dendrimers, nanoparticles, polymer networks, and advanced biomaterials.
Due to the excellent selectivity and efficiency of azide-based click chemistry, N3-PEG-N3 is widely employed in drug delivery, molecular imaging, biomaterials engineering, and bioconjugation applications.
Applications
- Click chemistry conjugation
- SPAAC conjugation
- CuAAC conjugation
- Hydrogel synthesis
- Nanoparticle functionalization
- Surface modification
- Polymer crosslinking
- Biomaterials engineering
- Molecular imaging
- Biomedical research
Features and Benefits
- Two terminal azide groups
- Homobifunctional PEG linker
- Compatible with CuAAC chemistry
- Compatible with SPAAC chemistry
- Excellent water solubility
- High biocompatibility
- Flexible PEG spacer
- Highly selective bioorthogonal reactions
- Available in multiple molecular weights
