PLLA-PEG-PLLA Diacrylate

Price range: $100.00 through $360.00

PLLA-PEG-PLLA Diacrylate is a biodegradable triblock copolymer consisting of poly(L-lactide) (PLLA) and polyethylene glycol (PEG) terminated with acrylate groups at both ends. The terminal acrylate functionalities readily undergo free-radical polymerization and thiol-Michael addition, making this macromer an excellent crosslinker for biodegradable hydrogels, tissue engineering, drug delivery, and regenerative medicine.

Product Name: PLLA-PEG-PLLA Diacrylate
Alternative Name: Acrylate-PLLA-PEG-PLLA-Acrylate
Chemical Structure: PLLA-PEG-PLLA Diacrylate
PLLA Molecular Weight: Custom available
PEG Molecular Weight: Custom available
Appearance: White to off-white powder
Solubility: DMSO, DMF, THF, acetone, dichloromethane; dispersible in aqueous media after crosslinking
Storage: -20°C, dry and protected from light
Purity: Typically ≥95%

Description

General Description

PLLA-PEG-PLLA Diacrylate is a difunctional amphiphilic triblock copolymer designed for the fabrication of biodegradable hydrogel networks and advanced biomedical materials. The hydrophobic PLLA end blocks provide biodegradability, mechanical strength, and controlled degradation, while the central PEG segment imparts excellent water solubility, flexibility, and biocompatibility.

The terminal acrylate groups enable rapid crosslinking through photopolymerization, thermal free-radical polymerization, or thiol-Michael addition, allowing the preparation of injectable hydrogels with tunable mechanical properties, swelling behavior, and degradation profiles.

PLLA-PEG-PLLA Diacrylate is widely used in tissue engineering, regenerative medicine, injectable scaffolds, cell encapsulation, drug delivery, bioinks for 3D bioprinting, wound healing, and controlled release applications. The combination of biodegradable polyester blocks and a hydrophilic PEG segment provides an ideal platform for developing next-generation biomaterials.

Applications

  • Injectable hydrogel synthesis
  • Tissue engineering
  • Regenerative medicine
  • Cell encapsulation
  • Drug delivery systems
  • Controlled drug release
  • Bioinks for 3D bioprinting
  • Wound healing materials
  • Surface modification
  • Biomaterials research

Features and Benefits

  • Biodegradable PLLA-PEG-PLLA triblock copolymer
  • Terminal diacrylate functionalities
  • Excellent biocompatibility
  • Efficient photo- and thermal crosslinking
  • Compatible with thiol-Michael addition
  • Tunable degradation and mechanical properties
  • Suitable for injectable hydrogels
  • Research-grade quality

Additional information

PLA Molecular weight

1000, 2000

PEG Molecular weight

1000, 2000, 3000

Package size

100mg, 1g