Poly(L-Ornithine)-MPEG

Poly(L-Ornithine)-MPEG

Price range: $380.00 through $1,200.00

Poly(L-Ornithine)-MPEG is a biocompatible polypeptide-polyethylene glycol copolymer consisting of poly(L-ornithine) and methoxy polyethylene glycol (mPEG). The poly(L-ornithine) segment provides multiple cationic amino groups for nucleic acid binding and cellular interactions, while the mPEG segment improves water solubility, biocompatibility, and colloidal stability. Poly(L-Ornithine)-MPEG is widely used in gene delivery, drug delivery, biomaterials engineering, and nanomedicine research.

Product Specifications

Product Name: Poly(L-Ornithine)-MPEG
Polymer Composition: Poly(L-Ornithine)-Methoxy Polyethylene Glycol
Molecular Weight: MPEG (1k, 2k, 5k, 10k Da), Poly(L-Ornithine) (5-200 repeating units), Custom
Functional Groups: mPEG, Primary Amines
Appearance: White to off-white solid
Solubility: Water, PBS, Aqueous Buffers
Storage: -20°C, dry and protected from light
Purity: Typically ≥95%

PEG-pOrn

 

SKU: 9544 Categories: ,

Description

General Description

Poly(L-Ornithine)-MPEG is an amphiphilic block copolymer that combines the cationic properties of poly(L-ornithine) with the hydrophilic and stealth characteristics of polyethylene glycol. Poly(L-ornithine) contains pendant primary amine groups capable of interacting with negatively charged nucleic acids, proteins, cell membranes, and biomolecules, making it useful for delivery and surface modification applications.

The mPEG segment enhances aqueous solubility, reduces nonspecific interactions, improves colloidal stability, and increases biocompatibility. Poly(L-Ornithine)-MPEG is frequently utilized for gene delivery systems, nucleic acid complexation, nanoparticle formulation, tissue engineering, and advanced biomaterials development.

Applications

  • Gene delivery
  • DNA delivery
  • mRNA delivery
  • siRNA delivery
  • Nucleic acid complexation
  • Nanoparticle formulation
  • Drug delivery systems
  • Surface modification
  • Tissue engineering
  • Biomaterials research

Features and Benefits

    • Cationic poly(L-ornithine) segment
    • Hydrophilic mPEG segment
    • Excellent water solubility
    • Multiple primary amine functionalities
    • Efficient nucleic acid binding
    • Improved biocompatibility
    • Enhanced colloidal stability
    • Reduced nonspecific interactions
    • Suitable for drug and gene delivery applications

Additional information

pOrn molecular weight

2000, 5000, 10K
PEG molecular weight

1000, 2000, 5000
package size

200mg, 500mg, 1g

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