Description
General Description
DSPE-PEG-Cy5 combines the membrane-anchoring capability of DSPE with the hydrophilic and biocompatible properties of PEG and the fluorescent characteristics of Cy5. The DSPE moiety readily inserts into lipid bilayers, while the PEG spacer improves aqueous dispersibility and minimizes nonspecific interactions. The Cy5 fluorophore exhibits excitation and emission in the near-infrared region, making it particularly useful for fluorescence imaging and nanoparticle tracking applications.
DSPE-PEG-Cy5 is widely utilized in drug delivery research, liposome labeling, extracellular vesicle studies, cellular uptake investigations, and in vivo biodistribution analysis.
Applications
- Fluorescent labeling of liposomes and lipid nanoparticles (LNPs)
- Nanoparticle tracking and biodistribution studies
- Drug delivery and nanomedicine research
- Cell uptake and intracellular trafficking studies
- Fluorescence microscopy and confocal imaging
- In vivo and ex vivo imaging applications
- Membrane labeling and lipid bilayer visualization
- Extracellular vesicle and exosome tracking
Features
- Near-infrared fluorescent Cy5 dye
- Efficient incorporation into lipid bilayers
- Enhanced aqueous stability through PEG spacer
- Excellent biocompatibility
- Suitable for fluorescence imaging and tracking studies
- Low nonspecific adsorption compared to non-PEGylated dyes
- Compatible with liposomes, micelles, and LNP formulations
