Description
General Description
4-Arm PEG-Epoxide is a branched PEG derivative designed for efficient crosslinking and bioconjugation applications. Compared with linear PEG derivatives, the four-arm architecture provides higher functional group density, enhanced crosslinking efficiency, and improved network formation.
The terminal epoxide groups undergo ring-opening reactions with primary amines, secondary amines, thiols, and hydroxyl-containing compounds under mild conditions, allowing formation of stable covalent linkages. The PEG backbone provides excellent water solubility, flexibility, biocompatibility, and resistance to nonspecific protein adsorption.
4-Arm PEG-Epoxide is widely employed in hydrogel preparation, tissue engineering scaffolds, injectable biomaterials, protein immobilization, cell encapsulation, surface functionalization, and advanced biomedical applications.
Applications
- Hydrogel synthesis
- Injectable hydrogels
- Tissue engineering
- Cell encapsulation
- Protein immobilization
- Surface modification
- Drug delivery systems
- Biomaterials engineering
- Crosslinking applications
- Biomedical research
Features and Benefits
- Four terminal epoxide groups
- Multi-arm PEG architecture
- High crosslinking efficiency
- Reactive toward amines and thiols
- Forms stable covalent linkages
- Excellent water solubility
- Excellent biocompatibility
- Low protein adsorption
- Available in multiple molecular weights
