Description
4-Arm PEG-Glutamic Acid is a branched PEG derivative designed for advanced biomaterials and bioconjugation applications. Compared with linear PEG derivatives, the four-arm architecture provides higher functional group density, enhanced crosslinking capability, and increased loading capacity for biologically active molecules.
The terminal glutamic acid residues introduce multiple carboxyl groups that can be activated using EDC/NHS chemistry for conjugation with proteins, peptides, antibodies, amine-containing polymers, nanoparticles, and biomaterial surfaces. The PEG backbone contributes excellent aqueous solubility, flexibility, biocompatibility, and reduced nonspecific protein adsorption.
4-Arm PEG-Glutamic Acid is frequently employed in hydrogel preparation, tissue engineering scaffolds, protein immobilization, drug delivery systems, surface modification, and regenerative medicine applications.
Applications
- Hydrogel synthesis
- Tissue engineering
- Drug delivery systems
- Protein conjugation
- Peptide conjugation
- Antibody conjugation
- Surface modification
- Nanoparticle functionalization
- Biomaterials engineering
- Biomedical research
Features and Benefits
- Four terminal glutamic acid groups
- Multiple carboxylic acid functionalities
- Multi-arm PEG architecture
- High functional group density
- Compatible with EDC/NHS coupling chemistry
- Excellent water solubility
- Excellent biocompatibility
- Low protein adsorption
- Available in multiple molecular weights
