Description
General Description
8-Arm PEG COOH is a multifunctional PEG derivative designed for the preparation of highly crosslinked biomaterials and advanced bioconjugates. The eight-arm architecture provides a high density of terminal carboxyl groups that can be readily activated using carbodiimide chemistry (EDC/NHS) for coupling to primary amines on proteins, peptides, antibodies, enzymes, polymers, and biomaterial surfaces.
The PEG backbone provides excellent water solubility, flexibility, biocompatibility, and minimizes nonspecific protein adsorption. Compared with linear PEG derivatives, the eight-arm architecture offers significantly higher conjugation efficiency and crosslinking density, making it particularly suitable for hydrogel fabrication, injectable biomaterials, tissue engineering scaffolds, and controlled drug delivery systems.
8-Arm PEG COOH is widely employed in hydrogel preparation, protein immobilization, nanoparticle functionalization, regenerative medicine, molecular imaging, polymer synthesis, and advanced biomaterials development.
Applications
- Hydrogel synthesis
- Protein conjugation
- Antibody conjugation
- Peptide conjugation
- Surface modification
- Nanoparticle functionalization
- Tissue engineering
- Drug delivery systems
- Regenerative medicine
- Biomaterials research
Features and Benefits
- Eight terminal carboxyl groups
- Multi-arm PEG architecture
- High coupling efficiency
- Compatible with EDC/NHS chemistry
- Excellent water solubility
- Excellent biocompatibility
- High crosslinking density
- Low protein adsorption
- Suitable for hydrogel fabrication
