DMPC phospholipid structure

DMPC

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DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine) is a high-purity saturated phospholipid widely used in liposome formulation, membrane biophysics, lipid bilayer studies, drug delivery, and biomedical research. Owing to its well-defined phase transition temperature and excellent membrane-forming properties, DMPC is one of the most widely used model phospholipids for membrane and liposome research.

Product Name: DMPC
Chemical Name: 1,2-Dimyristoyl-sn-glycero-3-phosphocholine
Abbreviation: DMPC
CAS Number: 18194-24-6
Molecular Formula: C<sub>36</sub>H<sub>72</sub>NO<sub>8</sub>P
Molecular Weight: 677.94 g/mol
Lipid Type: Phosphatidylcholine (PC)
Fatty Acid Composition: C14:0/C14:0
Phase Transition Temperature (Tm): ~23–24°C
Appearance: White to off-white powder
Purity: ≥99% (HPLC)
Solubility: Chloroform, Methanol, Chloroform/Methanol mixtures
Storage: -20°C, protected from moisture and light

DMPC phospholipid structure

 

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Product Details

CAS No. : 18194-24-6
Formula : C36H72NO8P
M.W : 677.93
SMILES Code : CCCCCCCCCCCCCC(O[C@@H](COP([O-])(OCC[N+](C)(C)C)=O)COC(CCCCCCCCCCCCC)=O)=O
Synonyms :
DMPC; Dimyristoyl phosphatidylcholine; 1,2-Dimyristoyl-sn-glycero-3-phosphorylcholine
English Name : (R)-2,3-Bis(tetradecanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
MDL No. : MFCD00036901
InChI Key : CITHEXJVPOWHKC-UUWRZZSWSA-N
Pubchem ID : 5459377

Description

General Description

DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) is a zwitterionic saturated phospholipid commonly used in liposome preparation, membrane biophysics, and lipid nanoparticle research. Due to its well-defined phase transition behavior and bilayer-forming capability, DMPC is widely utilized in biomembrane and pharmaceutical formulation studies.

Key Properties

  • Saturated phosphatidylcholine phospholipid
  • Forms stable lipid bilayers
  • Zwitterionic lipid material
  • Well-characterized phase transition behavior
  • Suitable for membrane and liposome applications

Applications

  • Liposome formulation
  • Biomembrane and membrane dynamics studies
  • Lipid bilayer model systems
  • Drug delivery research
  • Nanomedicine and biomaterial engineering
  • Pharmaceutical lipid formulation development

Functional Overview

DMPC forms organized lipid bilayers with reproducible thermal behavior, making it useful for membrane biophysics, liposome engineering, and advanced lipid formulation studies.

Summary

DMPC is a versatile saturated phospholipid widely used in liposome formulation, membrane studies, and pharmaceutical lipid research applications.

Additional information

Weight 1 lbs
Package Size

100mg, 200mg, 500mg, 1g, 5g

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