HSPC

Price range: $80.00 through $300.00

HSPC (Hydrogenated Soy Phosphatidylcholine) is a highly saturated phospholipid derived from hydrogenated soybean phosphatidylcholine. It is widely used as a structural lipid component in liposomes, lipid nanoparticles (LNPs), pharmaceutical formulations, and drug delivery systems. HSPC provides excellent membrane rigidity, enhanced stability, and prolonged circulation properties for lipid-based formulations.

Product Name: HSPC
Full Chemical Name: Hydrogenated Soy Phosphatidylcholine
Alternative Name: Hydrogenated Soy PC, Hydrogenated Soybean Phosphatidylcholine
Lipid Composition: Predominantly saturated phosphatidylcholine species
Appearance: White to off-white powder
Solubility: Chloroform, chloroform/methanol mixtures; limited aqueous solubility
Storage: -20°C, dry and protected from light
Purity: Typically ≥95%

HSPC phospholipid structure

 

SKU: 26372 Categories: ,

Product Details

Product Details of 1,2-Distearoyl-sn-glycero-3-phosphorylcholine

CAS No. : 97281-48-6
Formula : C42H84NO8P
M.W : 783.77
SMILES Code :  
Synonyms :
L-α-phosphatidylcholine, hydrogenated (Soy)
English Name : hydrogenated phosphatidylcholine 
MDL No. :  
   
   

Description

General Description

HSPC is a pharmaceutical-grade phospholipid widely employed in advanced lipid-based drug delivery systems. Through hydrogenation of natural soy phosphatidylcholine, unsaturated fatty acid chains are converted into saturated lipid chains, resulting in improved oxidative stability and increased membrane packing.

The highly saturated lipid structure provides a high phase transition temperature and forms rigid, stable lipid bilayers. This property makes HSPC particularly useful for preparing long-circulating liposomes and controlled-release lipid formulations.

HSPC is commonly combined with cholesterol and PEG-lipids such as DSPE-PEG derivatives to improve liposome stability, reduce aggregation, enhance circulation time, and optimize drug encapsulation performance. It has been extensively used in nanomedicine research, liposomal drug delivery, vaccine delivery systems, and pharmaceutical formulation development.

Applications

  • Liposome preparation
  • Lipid nanoparticle (LNP) formulation
  • Long-circulating liposomes
  • Drug delivery systems
  • Vaccine delivery research
  • Pharmaceutical formulations
  • Controlled-release systems
  • Nanomedicine research
  • Membrane model studies
  • Biomedical research

Features and Benefits

  • Highly saturated phospholipid
  • Excellent oxidative stability
  • High phase transition temperature
  • Forms stable lipid bilayers
  • Improves liposome rigidity
  • Compatible with cholesterol and PEG-lipids
  • Suitable for pharmaceutical formulations
  • Biocompatible lipid material

Additional information

Weight 1 lbs
Package Size

100mg, 200mg, 500mg, 1g, 5g