Description
General Description
DSPE-Rhodamine B (DSPE-RhB) is a fluorescent lipid probe designed for visualization and tracking of lipid-based nanoparticles and membrane systems. The DSPE lipid anchor consists of two saturated stearoyl (C18:0) hydrocarbon chains that enable stable incorporation into lipid bilayers, liposomes, and lipid nanoparticles.
The Rhodamine B fluorophore provides bright red fluorescence with excitation at approximately 540–560 nm and emission at approximately 570–590 nm, making it suitable for fluorescence microscopy, confocal imaging, flow cytometry, and fluorescence spectroscopy applications.
DSPE-Rhodamine B enables stable fluorescent labeling of liposomes and lipid nanoparticles for investigating cellular uptake, biodistribution, membrane interaction, and delivery mechanisms. It is widely used in targeted drug delivery research, molecular imaging, biosensors, and advanced nanomedicine applications.
Applications
- Fluorescent liposome labeling
- Lipid nanoparticle (LNP) imaging
- Membrane tracking
- Cellular uptake studies
- Fluorescence microscopy
- Confocal imaging
- Flow cytometry
- Nanoparticle biodistribution studies
- Drug delivery research
- Biomaterials research
Features and Benefits
- Bright Rhodamine B fluorescence
- Stable DSPE lipid anchor
- Efficient membrane incorporation
- Enables nanoparticle visualization
- Suitable for liposomes and LNPs
- Compatible with fluorescence analysis
- Useful for cellular uptake studies
- Biocompatible lipid probe
