PLLA-PEG-Rhodamine B (PLLA-PEG-RhB)

Price range: $300.00 through $480.00

PLLA-PEG-Rhodamine B (PLLA-PEG-RhB) is a fluorescent amphiphilic block copolymer consisting of poly(L-lactide) (PLLA), polyethylene glycol (PEG), and rhodamine B (RhB). The hydrophobic PLLA segment enables nanoparticle and micelle formation, the PEG spacer improves aqueous stability and biocompatibility, and the RhB fluorophore provides bright red fluorescence for imaging and tracking applications. PLLA-PEG-RhB is widely used in drug delivery research, nanoparticle tracking, cellular uptake studies, and biomaterials research.

Product Name: PLLA-PEG-Rhodamine B (PLLA-PEG-RhB)
Polymer Composition: Poly(L-lactide)-Polyethylene Glycol-Rhodamine B
PLLA Molecular Weight: 1k, 2k, 5k, 10k, 15k, 20k Da, Custom
PEG Molecular Weight: 1k, 2k, 3.4k, 5k, 10k Da
Fluorescent Label: Rhodamine B (RhB)
Excitation Wavelength: ~540–560 nm
Emission Wavelength: ~570–590 nm
Appearance: Pink to red solid
Solubility: DMSO, DMF, THF, Acetone, Chloroform, Dichloromethane
Storage: -20°C, protected from light
Purity: Typically ≥95%

PLA-PEG-RhB

Description

General Description

PLLA-PEG-Rhodamine B is a fluorescent biodegradable copolymer designed for imaging-enabled drug delivery and nanomedicine applications. The hydrophobic PLLA block self-assembles into nanoparticle cores capable of encapsulating hydrophobic drugs, while the PEG segment forms a hydrophilic corona that improves colloidal stability, prolongs circulation time, and reduces nonspecific protein adsorption.

The Rhodamine B label provides strong red fluorescence, allowing visualization and quantification of nanoparticles, micelles, and polymer systems using fluorescence microscopy, confocal microscopy, flow cytometry, fluorescence spectroscopy, and in vivo imaging techniques.

PLLA-PEG-RhB is widely employed in nanoparticle tracking, biodistribution studies, cellular uptake investigations, tissue engineering, molecular imaging, and advanced drug delivery research.

Applications

  • Nanoparticle tracking
  • Cellular uptake studies
  • Fluorescence imaging
  • Confocal microscopy
  • Flow cytometry
  • Biodistribution studies
  • Drug delivery research
  • Polymeric micelle preparation
  • Molecular imaging
  • Nanomedicine research

Features and Benefits

  • Bright red fluorescence
  • Biodegradable PLLA segment
  • Hydrophilic PEG spacer
  • Excellent nanoparticle formation capability
  • Suitable for in vitro and in vivo imaging
  • Enables nanoparticle tracking
  • Supports biodistribution studies
  • Excellent biocompatibility
  • Available in multiple PLLA and PEG molecular weights

Additional information

PLLA Molecular Weight

2000, 5000, 10K, 20K

PEG Molecular Weight

1000, 2000, 3000, 5000

Package size

50mg, 100mg