8 amr PEG-SS

8-arm PEG-SS

Price range: $300.00 through $1,200.00

8-arm PEG-SS is a multi-arm polyethylene glycol (PEG) derivative terminated with succinimidyl succinate (SS) groups. The activated NHS ester groups react rapidly and selectively with primary amines on proteins, peptides, antibodies, enzymes, and other biomolecules to form stable amide bonds. With eight highly reactive arms, 8-arm PEG-SS is an excellent macromolecular crosslinker for protein PEGylation, hydrogel synthesis, tissue engineering, drug delivery, and biomaterials research.

Product Name: 8-arm PEG-SS
Full Name: 8-arm Polyethylene Glycol Succinimidyl Succinate
Abbreviation: 8-arm PEG-SS
Chemical Structure: Eight-arm PEG terminated with succinimidyl succinate groups
PEG Molecular Weight: 10 kDa, 20 kDa, 40 kDa (custom molecular weights available)
Number of Arms: 8
Functional Group: Succinimidyl Succinate (SS)
Appearance: White to off-white powder
Solubility: Water, PBS, DMSO, DMF
Storage: -20°C, dry, moisture-free, and protected from light
Purity: Typically ≥95%

8 amr PEG-SS

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SKU: 2452 Categories: , ,

Description

General Description

8-arm PEG-SS is a branched PEG macromolecule functionalized with succinimidyl succinate (SS) groups at the terminus of each PEG arm. The terminal NHS ester groups readily react with primary amines under mild aqueous conditions (typically pH 7.2–8.5), producing stable amide linkages while preserving the biological activity of sensitive biomolecules.

The eight-arm architecture provides a high density of reactive sites, enabling efficient multivalent conjugation and the fabrication of highly crosslinked PEG hydrogel networks. Compared with linear PEG derivatives, 8-arm PEG-SS offers enhanced crosslinking efficiency, improved hydrogel mechanical strength, and greater flexibility for designing advanced biomaterials.

8-arm PEG-SS is widely employed in protein PEGylation, hydrogel fabrication, antibody conjugation, enzyme immobilization, tissue engineering, regenerative medicine, drug delivery, cell encapsulation, and surface functionalization.

Applications

  • Protein PEGylation
  • PEG hydrogel synthesis
  • Hydrogel crosslinking
  • Antibody conjugation
  • Enzyme immobilization
  • Cell encapsulation
  • Tissue engineering
  • Regenerative medicine
  • Drug delivery systems
  • Biomaterials research

Features and Benefits

  • Eight-arm PEG architecture
  • Terminal succinimidyl succinate (SS) groups
  • Highly reactive toward primary amines
  • Stable amide bond formation
  • High crosslinking efficiency
  • Excellent water solubility
  • Outstanding biocompatibility
  • Research-grade quality

Additional information

Molecular weight

10k, 20k, 40k
Package size

1g, 5g, 10g

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