Description
General Description
4-Arm PEG-Glutaric Acid is a branched PEG derivative functionalized with four terminal glutaric acid groups. Compared with linear PEG derivatives, the four-arm architecture provides higher functional group density, enhanced conjugation efficiency, and improved crosslinking capability.
The terminal carboxylic acid groups can be activated using EDC, NHS, DCC, or related coupling chemistries for conjugation with amine-containing peptides, proteins, antibodies, polymers, nanoparticles, and biomaterial surfaces. The glutaric acid spacer provides additional chain flexibility compared with direct carboxyl-functionalized PEG derivatives, which can improve accessibility and conjugation efficiency in certain applications.
The PEG backbone provides excellent water solubility, flexibility, biocompatibility, and resistance to nonspecific protein adsorption. 4-Arm PEG-Glutaric Acid is widely employed in hydrogel preparation, tissue engineering scaffolds, protein immobilization, drug delivery systems, nanoparticle functionalization, and advanced biomaterials development.
Applications
- Hydrogel synthesis
- Tissue engineering
- Drug delivery systems
- Protein conjugation
- Peptide conjugation
- Antibody conjugation
- Surface modification
- Nanoparticle functionalization
- Biomaterials engineering
- Biomedical research
Features and Benefits
- Four terminal glutaric acid groups
- Multi-arm PEG architecture
- Multiple reactive carboxylic acid groups
- Compatible with EDC/NHS coupling chemistry
- Flexible glutaric acid spacer
- High functional group density
- Excellent water solubility
- Excellent biocompatibility4-arm PEG-GAA
