BIO-PEG-FITC (Biotin-PEG-FITC)

Price range: $360.00 through $380.00

BIO-PEG-FITC (Biotin-PEG-FITC) is a heterobifunctional polyethylene glycol (PEG) derivative containing a biotin group at one terminus and fluorescein (FITC) at the other. The biotin moiety enables high-affinity binding to streptavidin and avidin, while FITC provides bright green fluorescence for imaging and detection. BIO-PEG-FITC is widely used in fluorescent labeling, molecular imaging, biosensors, diagnostics, and biomaterials research

Product Name: BIO-PEG-FITC (Biotin-PEG-FITC)
Alternative Name: Biotin-PEG-Fluorescein, FITC-PEG-Biotin
Molecular Weight: 1000, 2000, 3400, 5000, 10000 Da, Custom
Functional Groups: Biotin, PEG, FITC
Excitation Wavelength: ~495 nm
Emission Wavelength: ~519 nm
Appearance: Yellow to orange solid
Solubility: Water, PBS, DMSO, DMF
Storage: -20°C, dry and protected from light
Purity: Typically ≥95%
Biotin-PEG-FITC

Description

General Description

BIO-PEG-FITC is a multifunctional fluorescent PEG linker designed for affinity-based labeling and imaging applications. The terminal biotin group binds with exceptionally high affinity to streptavidin and avidin, enabling efficient immobilization, purification, and targeted delivery of biomolecules.

The FITC fluorophore provides strong green fluorescence for visualization by fluorescence microscopy, confocal microscopy, flow cytometry, fluorescence spectroscopy, and other fluorescence-based analytical techniques.

The hydrophilic PEG spacer improves water solubility, molecular flexibility, and biocompatibility while reducing steric hindrance and minimizing nonspecific protein adsorption. This design preserves the accessibility of both the biotin and FITC groups, making BIO-PEG-FITC an excellent reagent for fluorescent labeling, nanoparticle functionalization, biosensor fabrication, targeted drug delivery, and molecular imaging.

Applications

  • Fluorescent labeling
  • Protein labeling
  • Streptavidin-based assays
  • Antibody labeling
  • Molecular imaging
  • Flow cytometry
  • Confocal microscopy
  • Biosensor fabrication
  • Nanoparticle functionalization
  • Biomedical research

Features and Benefits

  • High-affinity biotin functionality
  • Bright FITC fluorescence
  • Hydrophilic PEG spacer
  • Excellent water solubility
  • Reduced steric hindrance
  • Low nonspecific protein adsorption
  • Excellent biocompatibility
  • Suitable for imaging and targeting
  • Available in multiple PEG molecular weights

Additional information

Molecular weight

1000, 2000, 3400, 5000

Package size

50 mg