Description
General Description
PLGA-Rhodamine B is a fluorescent biodegradable polyester prepared by covalently conjugating Rhodamine B to PLGA. The PLGA backbone retains the excellent biodegradability and biocompatibility of conventional PLGA, while the Rhodamine B fluorophore provides strong red fluorescence for sensitive optical detection.
PLGA-RhB can be formulated into nanoparticles, microspheres, implants, and injectable delivery systems while maintaining fluorescent labeling throughout fabrication. It is commonly used to investigate nanoparticle biodistribution, intracellular trafficking, drug release behavior, tissue penetration, and polymer degradation.
Applications
- Fluorescent nanoparticle preparation
- Cellular uptake studies
- Biodistribution studies
- Drug delivery research
- Bioimaging
- Confocal microscopy
- Microsphere preparation
- Tissue engineering
- Controlled drug release
- Biomaterials research
Features and Benefits
- Covalently labeled with Rhodamine B
- Bright red fluorescence
- Biodegradable PLGA backbone
- Excellent biocompatibility
- Suitable for nanoparticle fabrication
- Compatible with fluorescence microscopy
- Available in multiple PLGA compositions
- Research use only
