Description
General Description
4-Arm PEG-Succinic Acid is a branched PEG derivative functionalized with four terminal succinic acid groups. Compared with linear PEG derivatives, the four-arm architecture offers higher functional group density, enhanced conjugation efficiency, and improved crosslinking capability.
The terminal carboxylic acid groups can be activated using EDC, NHS, DCC, or related coupling chemistries for conjugation with amine-containing peptides, proteins, antibodies, polymers, nanoparticles, and biomaterial surfaces. The PEG backbone provides excellent water solubility, flexibility, biocompatibility, and resistance to nonspecific protein adsorption.
4-Arm PEG-Succinic Acid is widely employed in hydrogel preparation, tissue engineering scaffolds, protein immobilization, drug delivery systems, nanoparticle functionalization, and advanced biomaterials development.
Applications
- Hydrogel synthesis
- Tissue engineering
- Drug delivery systems
- Protein conjugation
- Peptide conjugation
- Antibody conjugation
- Surface modification
- Nanoparticle functionalization
- Biomaterials engineering
- Biomedical research
Features and Benefits
- Four terminal succinic acid groups
- Multi-arm PEG architecture
- Multiple reactive carboxylic acid groups
- Compatible with EDC/NHS coupling chemistry
- High functional group density
- Excellent water solubility
- Excellent biocompatibility
- Low protein adsorption
- Available in multiple molecular weights








