4-Arm PEG-Succinic Acid

Price range: $300.00 through $1,200.00

 

4-Arm PEG-Succinic Acid is a multi-arm polyethylene glycol derivative containing four terminal succinic acid groups attached to a central core. The terminal carboxylic acid functionalities provide multiple reactive sites for conjugation, crosslinking, and surface modification, making 4-Arm PEG-Succinic Acid an excellent material for hydrogel synthesis, drug delivery, tissue engineering, and biomaterials research.

Product Name: 4-Arm PEG-Succinic Acid
Alternative Name: 4-Arm PEG-SA
Polymer Architecture: Four-Arm Polyethylene Glycol
Core Structure: Pentaerythritol Based
Molecular Weight: 2k, 5k, 10k, 20k, 40k Da, Custom
Functional Groups: 4 × Succinic Acid
Appearance: White to off-white solid
Solubility: Water, PBS, DMSO, DMF
Storage: -20°C, dry and protected from light
Purity: Typically ≥95%

4-arm PEG-SA

 

Description

General Description

4-Arm PEG-Succinic Acid is a branched PEG derivative functionalized with four terminal succinic acid groups. Compared with linear PEG derivatives, the four-arm architecture offers higher functional group density, enhanced conjugation efficiency, and improved crosslinking capability.

The terminal carboxylic acid groups can be activated using EDC, NHS, DCC, or related coupling chemistries for conjugation with amine-containing peptides, proteins, antibodies, polymers, nanoparticles, and biomaterial surfaces. The PEG backbone provides excellent water solubility, flexibility, biocompatibility, and resistance to nonspecific protein adsorption.

4-Arm PEG-Succinic Acid is widely employed in hydrogel preparation, tissue engineering scaffolds, protein immobilization, drug delivery systems, nanoparticle functionalization, and advanced biomaterials development.

Applications

  • Hydrogel synthesis
  • Tissue engineering
  • Drug delivery systems
  • Protein conjugation
  • Peptide conjugation
  • Antibody conjugation
  • Surface modification
  • Nanoparticle functionalization
  • Biomaterials engineering
  • Biomedical research

Features and Benefits

  • Four terminal succinic acid groups
  • Multi-arm PEG architecture
  • Multiple reactive carboxylic acid groups
  • Compatible with EDC/NHS coupling chemistry
  • High functional group density
  • Excellent water solubility
  • Excellent biocompatibility
  • Low protein adsorption
  • Available in multiple molecular weights

Additional information

Molecular weight

2K, 5K, 10K, 20K

Package size

1g, 5g, 10g