Technical Data
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Name:Â Â DODMA
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Formula:C41H81NO2
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MW:620.1
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CAS:104162-47-2
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Purity:97%
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Ships Within:Â 24 Hours
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Storage Condition: -20°C
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Solubility:Â Ethanol, DMSO, DMF
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Shipping:Â Ambient Temperature
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Availability:Â In StokÂ
DODMA
Price range: $80.00 through $620.00
DODMA is a biodegradable ionizable lipid widely used in lipid nanoparticle (LNP) and liposome formulations for nucleic acid delivery. Due to its pH-responsive ionizable amine functionality, DODMA efficiently complexes with nucleic acids under acidic conditions while remaining largely neutral at physiological pH, making it a valuable component for siRNA, mRNA, DNA, and gene delivery applications.
Product Name: DODMA
Full Name: 1,2-Dioleyloxy-N,N-dimethyl-3-aminopropane
Molecular Weight: 620.1 g/mol
CAS Number: 104162-47-2
Appearance: Colorless to pale yellow oil or waxy solid
Purity: Typically ≥95%
Storage: -20°C, dry and protected from light
Full Name: 1,2-Dioleyloxy-N,N-dimethyl-3-aminopropane
Molecular Weight: 620.1 g/mol
CAS Number: 104162-47-2
Appearance: Colorless to pale yellow oil or waxy solid
Purity: Typically ≥95%
Storage: -20°C, dry and protected from light
Description
General Description
DODMA is a synthetic cationic lipid widely used in lipid nanoparticle (LNP) and liposome formulation research. Its tertiary amine headgroup enables electrostatic interaction with negatively charged nucleic acids, supporting efficient encapsulation and intracellular delivery.
Key Properties
- Cationic lipid for nucleic acid delivery
- Suitable for lipid nanoparticle (LNP) formulation
- Promotes RNA and DNA complexation
- Hydrophobic lipid tails support membrane interaction
- Commonly used in gene delivery research
Applications
- Lipid nanoparticle formulation
- Gene and nucleic acid delivery
- siRNA and mRNA delivery systems
- Liposome preparation
- Nanomedicine and drug delivery research
- Non-viral transfection studies
Functional Overview
DODMA contains an ionizable/cationic amine functionality that interacts with nucleic acids during nanoparticle formulation, facilitating encapsulation and intracellular transport.
Summary
DODMA is a widely used cationic lipid for lipid nanoparticle and gene delivery research applications.
Additional information
| Package Size | 50mg, 100mg, 250mg, 500mg, 1g |
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